« Previous
Next »
Seminars in Nephrology
Volume 24, Issue 2
, Pages 158-167
, March 2004
Angiotensin-converting enzyme inhibition and angiotensin II antagonism in nondiabetic chronic nephropathies
References
-
.
The renin-angiotensin system in progression, remission and regression of chronic nephropathies.
J Hypertens. 2002;20(suppl):S45–S53
- Role of abnormally high transmural pressure in the permselectivity defect of glomerular capillary wall (A study in early passive Heymann nephritis). Circ Res. 1987;61:531–538
- . Mechanism of angiotensin II-induced proteinuria in the rat. Am J Physiol. 1977;233:F13–F21
- A II modulates glomerular capillary permselectivity in rat isolated perfused kidney. J Am Soc Nephrol. 1996;7:653–660
- A role for podocytes to counteract capillary wall distension. Kidney Int. 1994;45:369–376
-
.
A II induces actin polymerization within the glomerular filtration barrier (Possible role in the local regulation of ultrafiltration).
J Am Soc Nephrol. 1992;3:568;
(abstract)
- A II depolarizes podocytes in the intact glomerulus of the rat. J Clin Invest. 1997;99:2772–2781
- . Pathophysiology of progressive nephropathies. N Engl J Med. 1998;339:1448–1456
- Transforming growth factor-beta1 is up-regulated by podocytes in response to excess intraglomerular passage of proteins (A central pathway in progressive glomerulosclerosis). Am J Pathol. 2002;161:2179–2199
- Age-related nephropathy and proteinuria in rats with intact kidneys exposed to diets with different protein content. Lab Invest. 1989;60:196–204
- Tubulointerstitial lesions mediate renal damage in adriamycin glomerulopathy. Kidney Int. 1986;30:488–496
-
.
Proteinuria and phenotypic change of proximal tubular cells.
J Am Soc Nephrol. 2003;14:S36–S41
- . Nuclear factor-kB—A pivotal transcription factor in chronic inflammatory diseases. N Engl J Med. 1997;336:1066–1071
- . The transcription factor NF-kB and human disease. J Clin Invest. 2001;107:3–11
- Protein overload stimulates RANTES production by proximal tubular cells depending on NF-kB activation. Kidney Int. 1998;53:1608–1615
- Protein overload-induced NF-kB activation in proximal tubular cells requires H202 through a PKC-dependent pathway. J Am Soc Nephrol. 2002;13:1179–1189
- Tubular NF-kB and AP-1 activation in human proteinuric renal disease. Kidney Int. 2001;60:1366–1377
- . Role of cellular infiltrates in response to proteinuria. Am J Kidney Dis. 2001;37(Suppl 2):S25–S29
- Paracrine stimulation of human renal fibroblasts by proximal tubule cells. Kidney Int. 1998;54:747–757
- . Cellular responses to protein overload (Key event in renal disease). Curr Opin Nephrol Hypertens. 2004;13:31–37
- . Chronic progression of tubulointerstitial damage in proteinuric renal disease is mediated by complement activation (A therapeutic role for complement inhibitors?). J Am Soc Nephrol. 2003;14:S186–S191
- . A II as a mediator of tubulointerstitial injury. Nephrol Dial Transplant. 2000;15(suppl):61–63
- . Renal tubular hypertrophy induced by A II. Semin Nephrol. 1997;17:448–454
-
A II induces alpha3 (IV) collagen expression in cultured urine proximal tubular cells.
Proc Assoc Am Physic. 1999;11:357–364
- . Interstitial pathomechanisms underlying progressive tubulointerstitial damage. Kidney Blood Press Res. 1999;22:71–80
- ECM degradation by cultured human mesangial cells is mediated by a PA/plasmin/MMP-2 cascade. Kidney Int. 1995;47:1039–1047
- . Relationship among altered glomerular barrier permselectivity. A II, and mesangial uptake of macromolecules. Lab Invest. 1985;52:599–604
- . Vasoactive hormones and renal sclerosis. Kidney Int. 1996;49:578–597
- Early role of Fsp 1 in epithelial-mesenchymal transformation. Am J Physiol. 1997;273:F563–F574
-
Targeted deletion of Angiotensin II type 1 receptor does not protect mice from progressive nephropathy of overload proteinuria.
J Am Soc Nephrol. 2002;13:341;
(abstract)
- Prevention of diabetic glomerulopathy by pharmacological amelioration of glomerular capillary hypertension. J Clin Invest. 1986;77:1925–1930
- Angiotensin converting enzyme inhibition ameliorates glomerular filtration of macromolecules and water and lessens glomerular injury in the rat. J Clin Invest. 1990;85:541–549
- Protein traffic activates NF-kB gene signaling and promotes MCP-1-dependent interstitial inflammation. Am J Kidney Dis. 2000;36:1226–1241
- . Renoprotective benefits of RAS inhibitionFro ACEi to angiotensin II antagonists. Kidney Int. 2000;57:1803–1817
- Effect of the angiotensin-converting-enzyme inhibitor benazepril on the progression of chronic renal insufficiency. The Angiotensin-Converting-Enzyme Inhibition in Progressive Renal I Study Group. N Engl J Med. 1996;334:939–945
- . Randomised placebo-controlled trial of effect of ramipril on decline in glomerular filtration rate and risk of terminal renal failure in proteinuric, non-diabetic nephropathy. Lancet. 1997;349:1857–1863
- Renal function and requirement for dialysis in chronic nephropathy patients on long-term ramipril (REIN follow-up trial). Lancet. 1998;352:1252–1256
- Renoprotective properties of ACE-inhibition in non-diabetic nephropathies with non-nephrotic proteinuria. Lancet. 1999;354:359–364
- . Retarding progression of chronic renal disease (The neglected issue of residual proteinuria). Kidney Int. 2003;63:2254–2261
- . ACE inhibitors to prevent end-stage renal disease: When to start and why possibly never to stop: A post hoc analysis of the REIN trial result. Ramipril Eficacy in Nephropathy. J Am Soc Nephrol. 2001;12:2832–2837
-
.
Effects of an angiotensin converting enzyme inhibitor on residual renal function in patients receiving peritoneal dialysis.
Ann Intern Med. 2003;139:105–112
- African American Study of Kidney Disease and Hypertension (AASK) Study Group: Effect of ramipril vs amlodipine on renal outcomes in hypertensive nephrosclerosis: A randomized controlled trial. JAMA. 2001;285:2719–2728
- Effect of blood pressure lowering and antihypertensive drug class on progression of hypertensive kidney disease (Results from the AASK trial). JAMA. 2002;288:2421–2431
- In chronic nephropathies prolonged ACE inhibition can induce remission (Dynamics of time-dependent changes in GFR). J Am Soc Nephrol. 1999;10:997–1006
- ACE inhibition induces regression of proteinuria and halts progression of renal damage in a genetic model of progressive nephropathy. Am J Kidney Dis. 1999;34:626–632
- Cause of variable therapeutic efficiency of angiotensin converting enzyme inhibitor on glomerular lesions. Kidney Int. 1991;40:195–202
- Regression of sclerosis in aging by an angiotensin inhibition-induced decrease in PAI-1. Kidney Int. 2000;58:2425–2436
- Diverse effects of increasing Lisinopril doses on lipid abnormalities in chronic nephropathies. Circulation. 2003;107:586–592
- . Combination ACEi and ARB therapy (Additional benefit in renoprotection?). Curr Opin Nephrol Hypertens. 2002;11:377–381
-
Ruggenenti P, Remuzzi G. Is therapy with combined ACE inhibitor and angiotensin receptor antagonist the new “gold standard” of treatment for non-diabetic chronic proteinuric nephropathies? Nephrology (in press)
- Effect of A II antagonism on the regression of kidney disease in the rat. Kidney Int. 2002;62:885–894
- How to fully protect the kidney in a severe model of progressive nephropathy (A multidrug approach). J Am Soc Nephrol. 2002;13:2898–2908
- Effects of combined ACE inhibitor and angiotensin II antagonist treatment in human chronic nephropathies. Kidney Int. 2003;63:1094–1103
- Combination treatment of angiotensin II receptor blocker and angiotensin converting enzyme inhibitor in non diabetic renal disease (COOPERATE) (A randomized controlled trial). Lancet. 2003;361:117–124
- Effect of combining ACE inhibitor and statin in severe experimental nephropathy. Kidney Int. 2002;61:1635–1645
- Disruption of tissue-type plasminogen activator gene in mice reduces renal interstitial fibrosis in obstructive nephropathy. J Clin Invest. 2002;110:1525–1538
-
Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-β antibody in db/db diabetic mice.
Proc Natl Acad Sci USA. 2000;97:8015–8020
- Vasopeptidase inhibition affords greater renoprotection than angiotensin-converting enzyme inhibition alone. J Am Soc Nephrol. 2001;12:2051–2059
- Combining an antiproteinuric approach with micophenolate mofetil fully suppresses progressive nephropathy of experimental animals. J Am Soc Nephrol. 1999;10:1542–1549
- . C6 mediates chronic progression of tubulointerstitial damage in rats with remnant kidneys. J Am Soc Nephrol. 2002;13:928–936
- Immunosuppressive treatment protects against A II-induced renal damage. Am J Pathol. 2002;161:1679–1693
- . Progression, remission, regression of chronic renal diseases. Lancet. 2001;357:1601–1608
- . Remission achieved in chronic nephropathy by a multidrug approach targeted at urinary protein excretion. Nephron. 2001;88:254–259
- Reversal of lesions of diabetic nephropathy after pancreas transplantation. N Engl J Med. 1998;339:69–75
- Evidence that an angiotensin converting enzyme inhibitor has a different effect on glomerular injury according to the different phase of the disease at which the treatment is started. J Am Soc Nephrol. 1994;5:1139–1146
- Slowing the progression of chronic renal failure (Economic benefits and patients’ perspectives). Am J Kidney Dis. 2002;39:721–729
- . Abnormalities of kidney function as a cause and a consequence of cardiovascular disease. Am J Med Sci. 1999;317:176–182
- . The clinical epidemiology of cardiac disease in chronic renal failure. J Am Soc Nephrol. 1999;10:1606–1615
- Renal insufficiency as a predictor of cardiovascular outcomes and the impact of Ramipril (The HOPE randomized trial). Ann Intern Med. 2001;134:629–636
- . Premature cardiovascular disease in chronic renal failure. Lancet. 2000;356:147–152
- Early increase in blood pressure and diastolic left ventricular malfunction in patients with glomerulonephritis. Kidney Int. 1996;50:1321–1326
- Apolipoprotein A-IV serum concentrations are elevated in patients with mild and moderate renal failure. J Am Soc Nephrol. 2000;11:105–115
- Sustained reduction of hyperhomocysteinaemia with folic acid supplementation in predialysis patients. Nephrol Dial Transplant. 1999;14:2903–2906
- Insulin resistance and hyperinsulinemia are already present in patients with incipient renal disease. Kidney Int. 1998;53:1343–1347
- . Albuminuria and poor glycemic control predict mortality in NIDD?. Diabetes. 1995;44:1303–1309
-
.
Anti-ischemic effects of ACE-inhibitors (Review of current clinical evidence and ongoing trials).
Eur Heart J. 1998;19:J36–J44
- . Secondary prevention of renal and cardiovascular disease (Results of a renal and cardiovascular treatment program in an Australian Aboriginal community). J Am Soc Nephrol. 2003;14:S178–S185
- . Effects of angiotensin converting enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. N Engl J Med. 2000;342:145–153
-
.
Pharmacotherapy for heart failure in patients with renal insufficiency.
Ann Intern Med. 2003;138:917–924
PII: S0270-9295(03)00192-X
doi: 10.1016/j.semnephrol.2003.11.002
© 2004 Elsevier Inc. All rights reserved.
« Previous
Next »
Seminars in Nephrology
Volume 24, Issue 2
, Pages 158-167
, March 2004
