Seminars in Nephrology
Volume 27, Issue 6 , Pages 621-626 , November 2007

Calorimetric Analysis of the Plasma Proteome

  • Nichola C. Garbett, PhD

      Affiliations

    • James Graham Brown Cancer Center, Department of Medicine, University of Louisville Health Sciences Center, Louisville, KY.
    • ,
  • James J. Miller, PhD

      Affiliations

    • Department of Pathology & Laboratory Medicine, University of Louisville Health Sciences Center, Louisville, KY.
    • ,
  • A. Bennett Jenson, MD

      Affiliations

    • James Graham Brown Cancer Center, Department of Medicine, University of Louisville Health Sciences Center, Louisville, KY.
    • ,
  • Jonathan B. Chaires, PhD

      Affiliations

    • James Graham Brown Cancer Center, Department of Medicine, University of Louisville Health Sciences Center, Louisville, KY.
    • Corresponding Author InformationAddress reprint requests to Jonathan B. Chaires, PhD, James Graham Brown Cancer Center, University of Louisville Health Sciences Center, 529 S Jackson St, Louisville, KY 40202.

References 

  1. Craig W, Ledue T, Ritchie R. Plasma proteins: clinical utility and interpretation. Scarborough, ME: Foundation for Blood Research; 2004;
  2. O’Connell TX, Horita TJ, Kasravi B. Understanding and interpreting serum protein electrophoresis. Am Fam Physician. 205;71:105-12.
  3. Anderson NL, Anderson NG. The human plasma proteome: history, character, and diagnostic prospects. Mol Cell Proteomics. 2002;1:845–867
  4. Anderson NL, Polanski M, Pieper R, et al. The human plasma proteome: a nonredundant list developed by combination of four separate sources. Mol Cell Proteomics. 2004;3:311–326
  5. Omenn GS, States DJ, Adamski M, et al. Overview of the HUPO Plasma Proteome Project: results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly-available database. Proteomics. 2005;5:3226–3245
  6. Anderson NL. The roles of multiple proteomic platforms in a pipeline for new diagnostics. Mol Cell Proteomics. 2005;4:1441–1444
  7. Gygi SP, Aebersold R. Mass spectrometry and proteomics. Curr Opin Chem Biol. 2000;4:489–494
  8. Liotta LA, Kohn EC, Petricoin EF. Clinical proteomics: personalized molecular medicine. JAMA. 2001;286:2211–2214
  9. Yates I. Mass spectrometry (From genomics to proteomics). Trends Genet. 2000;16:5–8
  10. Adkins JN, Varnum SM, Auberry KJ, et al. Toward a human blood serum proteome: analysis by multidimensional separation coupled with mass spectrometry. Mol Cell Proteomics. 2002;1:947–955
  11. Anderson L, Anderson NG. High resolution two-dimensional electrophoresis of human plasma proteins. Proc Natl Acad Sci U S A. 1977;74:5421–5425
  12. Anderson NL, Anderson NG. A two-dimensional gel database of human plasma proteins. Electrophoresis. 1991;12:883–906
  13. Liotta LA, Petricoin EF. Serum peptidome for cancer detection: spinning biologic trash into diagnostic gold. J Clin Invest. 2006;116:26–30
  14. Liotta LA, Ferrari M, Petricoin E. Clinical proteomics: written in blood. Nature. 2003;425:905
  15. Zhou M, Lucas DA, Chan KC, et al. An investigation into the human serum “interactome”. Electrophoresis. 2004;25:1289–1298
  16. Biltonen RL, Freire E. Thermodynamic characterization of conformational states of biological macromolecules using differential scanning calorimetry. CRC Crit Rev Biochem. 1978;5:85–124
  17. Brandts JF, Lin L-N. Study of strong to ultratight protein interactions using differential scanning calorimetry. Biochemistry. 1990;29:6927–6940
  18. Bruylants G, Wouters J, Michaux C. Differential scanning calorimetry in life science: thermodynamics, stability, molecular recognition and application in drug design. Curr Med Chem. 2005;12:2011–2020
  19. Freire E. Differential scanning calorimetry. Methods Mol Biol. 1995;40:191–218
  20. Sanchez-Ruiz JM. Differential scanning calorimetry of proteins. Subcell Biochem. 1995;24:133–176
  21. Schellman JA. The factors affecting the stability of hydrogen-bonded polypeptide structures in solution. J Phys Chem. 1958;62:1485–1494

 Supported by grant R44 CA103437 from the National Cancer Institute (J.B.C.).

PII: S0270-9295(07)00128-3

doi: 10.1016/j.semnephrol.2007.09.004

Seminars in Nephrology
Volume 27, Issue 6 , Pages 621-626 , November 2007

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