Seminars in Nephrology
Volume 28, Issue 4 , Pages 373-382, July 2008

Nephrotoxicity of Insect and Spider Venoms in Latin America

  • Regina C.R.M. Abdulkader, MD, PhD

      Affiliations

    • Laboratory of Renal Physiopathology, School of Medicine, University of São Paulo, São Paulo, Brazil.
    • Corresponding Author InformationAddress reprint requests to Regina C. R. M. Abdulkader, Laboratório de Fisiopatologia Renal, LIM 16, Faculdade de Medicina da Universidade de São Paulo, Av. Dr. Arnaldo, 455, Sala 3342, Cerqueira César, 01246-903 São Paulo, SP, Brazil.
    • ,
  • Katia C. Barbaro, PhD

      Affiliations

    • Laboratory of Immunopathology, Butantan Institute, São Paulo, Brazil.
    • ,
  • Elvino José Guradão Barros, MD, PhD

      Affiliations

    • Department of Internal Medicine, Federal University of Rio Grande do Sul School of Medicine, Porto Alegre, Brazil.
    • ,
  • Emmanuel A. Burdmann, MD, PhD

      Affiliations

    • Division of Nephrology, São José do Rio Preto Medical School, São Paulo, Brazil.

Summary 

One of the most important and lethal effects of animal venoms is nephrotoxicity. In Latin America, severe acute kidney injury has been reported after accidents with poisonous arthropods such as bees, caterpillars of the genus Lonomia, and spiders of the genus Loxosceles. In this article the characteristics of these venoms, their probable mechanisms of renal damage, and the clinical picture of the accidents are reviewed.

Keywords: Acute kidney injury, acute renal failure, nephrotoxicity, bees, caterpillars, Lonomia, spiders, Loxosceles

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 Supported in part by grants from the Foundation for the Support of Research in the State of São Paulo (Fundação de Amparo à Pesquisa do Estado de São Paulo) and from the National Council for Scientific and Technological Development (Conselho Nacional de Desenvolvimento Científico e Tecnológico) (E.A.B. and K.C.B.).

PII: S0270-9295(08)00084-3

doi:10.1016/j.semnephrol.2008.04.006

Seminars in Nephrology
Volume 28, Issue 4 , Pages 373-382, July 2008

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