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Seminars in Nephrology
Volume 29, Issue 2
, Pages 113-121
, March 2009
Role of Vitamin D in Chronic Kidney Disease
References
- Relation between renal dysfunction and cardiovascular outcomes after myocardial infarction. N Engl J Med. 2004;351:1285–1295
- USRDS morbidity and mortality 2007 data. [cited 2008 August 15]. Available from: http://www.usrds.org/2007/pdf/06_hosp_morte_07.pdf.
- . Predictors of cardiovascular death in ESRD. Semin Nephrol. 2005;25:358–362
- K/DOQI clinical practice guidelines for bone metabolism and disease in chronic kidney disease. Am J Kidney Dis. 2003;42:S1–S201
- . Vitamin D analogs: actions and role in the treatment of secondary hyperparathyroidism. Semin Nephrol. 2004;24:456–459
- . The discovery of vitamin D: the contribution of Adolf Windaus. J Nutr. 2004;134:1299–1302
- . Marked suppression of secondary hyperparathyroidism by intravenous administration of 1,25-dihydroxy-cholecalciferol in uremic patients. J Clin Invest. 1984;74:2136–2143
- . Site of 1,25(OH)2 vitamin D3 synthesis in the kidney. Nature. 1978;276:287–289
- . New insights into the mechanisms of vitamin D action. J Cell Biochem. 2003;88:695–705
- . Klotho as a regulator of oxidative stress and senescence. Biol Chem. 2008;389:233–241
- Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Nature. 1997;390:45–51
- Homozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis, and reverses hypophosphatemia in Phex-deficient mice. Matrix Biol. 2004;23:421–432
- Fibroblast growth factor 23 is a counter-regulatory phosphaturic hormone for vitamin D. J Am Soc Nephrol. 2006;17:1305–1315
- Fibroblast growth factor-23 regulates parathyroid hormone and 1alpha-hydroxylase expression in cultured bovine parathyroid cells. J Endocrinol. 2007;195:125–131
- . Emerging role of fibroblast growth factor 23 in a bone-kidney axis regulating systemic phosphate homeostasis and extracellular matrix mineralization. Curr Opin Nephrol Hypertens. 2007;16:329–335
- Fibroblast growth factor 23 (FGF23) predicts progression of chronic kidney disease: the Mild to Moderate Kidney Disease (MMKD) Study. J Am Soc Nephrol. 2007;18:2600–2608
- fibroblast growth factor 23 and mortality among patients undergoing hemodialysis. N Engl J Med. 2008;359:584–592
- . Does Fgf23-klotho activity influence vascular and soft tissue calcification through regulating mineral ion metabolism?. Kidney Int. 2008;74:566–570
- . Klotho: an antiaging protein involved in mineral and vitamin D metabolism. Kidney Int. 2007;71:730–737
- Lower risk for cardiovascular mortality in oral 1alpha-hydroxy vitamin D3 users in a haemodialysis population. Nephrol Dial Transplant. 2004;19:179–184
- Mortality risk among hemodialysis patients receiving different vitamin D analogs. Kidney Int. 2006;70:1858–1865
- Changes in serum calcium, phosphate, and PTH and the risk of death in incident dialysis patients: a longitudinal study. Kidney Int. 2006;70:351–357
- . Survival of patients undergoing hemodialysis with paricalcitol or calcitriol therapy. N Engl J Med. 2003;349:446–456
- Activated injectable vitamin D and hemodialysis survival: a historical cohort study. J Am Soc Nephrol. 2005;16:1115–1125
- . Meta-analysis: vitamin D compounds in chronic kidney disease. Ann Intern Med. 2007;147:840–853
- . Activated vitamin D sterols in kidney disease. Lancet. 2008;371:542–544
- . Association of activated vitamin D treatment and mortality in chronic kidney disease. Arch Intern Med. 2008;168:397–403
- . Association of oral calcitriol with improved survival in nondialyzed CKD. J Am Soc Nephrol. 2008;19:1613–1619
- Coronary-artery calcification in young adults with end-stage renal disease who are undergoing dialysis. N Engl J Med. 2000;342:1478–1483
- . Soft tissue calcification in pediatric patients with end-stage renal disease. Kidney Int. 1990;38:931–936
- . Vascular calcification in long-term haemodialysis patients in a single unit: a retrospective analysis. Nephron. 1997;77:37–43
- . Arterial calcification after vitamin D. Lancet. 1969;1:416
- . Ultrastructural study of hypervitaminosis D induced arterial calcification in Wistar rats. Artery. 1988;16:51–61
- Active serum vitamin D levels are inversely correlated with coronary calcification. Circulation. 1997;96:1755–1760
- . Vitamin D in chronic kidney disease: a systemic role for selective vitamin D receptor activation. Kidney Int. 2006;69:33–43
- 1,25-(OH)2-vitamin D3 suppresses the bone-related Runx2/Cbfa1 gene promoter. Exp Cell Res. 2002;274:323–333
- . Vitamin D receptor activators can protect against vascular calcification. J Am Soc Nephrol. 2008;19:1509–1519
- . Differential effects of vitamin D analogs on vascular calcification. J Bone Miner Res. 2007;22:860–866
- Differential effects of vitamin D receptor activators on aortic calcification and pulse wave velocity in uraemic rats. Nephrol Dial Transplant. 2008;23:3824–3830
- . Calciphylaxis is usually non-ulcerating: risk factors, outcome and therapy. Kidney Int. 2002;61:2210–2217
- . Calciphylaxis from nonuremic causes: a systematic review. Clin J Am Soc Nephrol. 2008;3:1139–1143
- . Clinical epidemiology of cardiac disease in dialysis patients: left ventricular hypertrophy, ischemic heart disease, and cardiac failure. Semin Dial. 2003;16:111–117
- Association of vitamin D deficiency with heart failure and sudden cardiac death in a large cross-sectional study of patients referred for coronary angiography. J Clin Endocrinol Metab. 2008;93:3927–3935
- Cardiac hypertrophy in vitamin D receptor knockout mice: role of the systemic and cardiac renin-angiotensin systems. Am J Physiol Endocrinol Metab. 2005;288:E125–E132
- Activated vitamin D attenuates left ventricular abnormalities induced by dietary sodium in Dahl salt-sensitive animals. Proc Natl Acad Sci U S A. 2007;104:16810–16815
- . Targeted ablation of the vitamin D 1alpha-hydroxylase gene: getting to the heart of the matter. Kidney Int. 2008;74:141–143
- . Calcium-independent and 1,25(OH)2D3-dependent regulation of the renin-angiotensin system in 1alpha-hydroxylase knockout mice. Kidney Int. 2008;74:170–179
- Effect of paricalcitol and calcitriol on cardiovascular disease in uninephrectomized ApoE knockout mice. Paper presented at: American Society of Nephrology Annual Meeting; 2007;Nov 2-5; San Francisco, CA
- . Vitamin D supplementation improves cytokine profiles in patients with congestive heart failure: a double-blind, randomized, placebo-controlled trial. Am J Clin Nutr. 2006;83:754–759
- Intravenous calcitriol regresses myocardial hypertrophy in hemodialysis patients with secondary hyperparathyroidism. Am J Kidney Dis. 1999;33:73–81
- . Specific binding of 1alpha,25-dihydroxycholecalciferol to nuclear components of chick intestine. J Biol Chem. 1975;250:1588–1594
- . Deficiencies of 25D, 1,25D and inflammation are associated with albuminuria. Paper presented at: American Society of Nephrology Annual Meeting; 2007;Nov 2-5; San Francisco, CA
- Antiproteinuric effect of oral paricalcitol in chronic kidney disease. Kidney Int. 2005;68:2823–2828
- Paricalcitol reduces albuminuria and inflammation in chronic kidney disease: a randomized double-blind pilot trial. Hypertension. 2008;52:249–255
- Effects of 1,25(OH)2D3 in experimental mesangial proliferative nephritis in rats. Kidney Int. 2001;60:87–95
- 1,25-dihydroxyvitamin D3 decreases podocyte loss and podocyte hypertrophy in the subtotally nephrectomized rat. Am J Physiol Renal Physiol. 2004;286:F526–F533
- A vitamin D analog ameliorates glomerular injury on rat glomerulonephritis. Am J Pathol. 2001;158:1733–1741
- . Therapeutic role and potential mechanisms of active vitamin D in renal interstitial fibrosis. J Steroid Biochem Mol Biol. 2007;103:491–496
- [cited 2008 June 9]. Available from: http://nobelprize.org/nobel_prizes/medicine/laureates/1929/.
- . Incidence of infectious morbidity and mortality in dialysis patients. Blood Purif. 2002;20:477–480
- . Vitamin D and the immune system: role in protection against bacterial infection. Curr Opin Nephrol Hypertens. 2008;17:348–352
- Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science. 2006;311:1770–1773
- . Are chronic dialysis patients at increased risk for cancer?. J Nephrol. 2008;21:166–174
- . Calcitriol in cancer treatment: from the lab to the clinic. Mol Cancer Ther. 2004;3:373–381
- . Vitamin D and vitamin D analogs as cancer chemopreventive agents. Nutr Rev. 2003;61:227–238
- Beneficial effect of the active form of vitamin D3 against LPS-induced DIC but not against tissue-factor-induced DIC in rat models. Thromb Haemost. 2001;85:287–290
- Disruption of nuclear vitamin D receptor gene causes enhanced thrombogenicity in mice. J Biol Chem. 2004;279:35798–35802
- Pathogenic mechanisms for parathyroid hyperplasia. Kidney Int Suppl. 2006;S8-1
- EGFR activation increases parathyroid hyperplasia and calcitriol resistance in kidney disease. J Am Soc Nephrol. 2008;19:310–320
- . Contribution of reduced parathyroid vitamin D receptor (VDR) to the switch from diffuse to nodular growth in secondary hyperparathyroidism. Paper presented at: American Society of Nephrology Annual Meeting; 2007;Nov 2-5; San Francisco, CA
- . Prevalence of vitamin D [25(OH)D] deficiency and effects of supplementation with ergocalciferol (vitamin D2) in stage 5 chronic kidney disease patients. J Ren Nutr. 2008;18:375–382
- Hypovitaminosis D in chronic kidney disease. Clin J Am Soc Nephrol. 2008;3:1144–1151
- High-dose cholecalciferol to correct vitamin D deficiency in haemodialysis patients. Nephrol Dial Transplant. 2008;23:4016–4020
- Cholecalciferol (vitamin D3) therapy and vitamin D insufficiency in patients with chronic kidney disease: a randomized controlled pilot study. Endocr Pract. 2008;14:10–17
- . 25-Hydroxyvitamin D, insulin resistance, and kidney function in the Third National Health and Nutrition Examination Survey. Kidney Int. 2007;71:134–139
- Vitamin D deficiency and risk of cardiovascular disease. Circulation. 2008;117:503–511
- Prevalence of cardiovascular risk factors and the serum levels of 25-hydroxyvitamin D in the United States: data from the Third National Health and Nutrition Examination Survey. Arch Intern Med. 2007;167:1159–1165
- . Vitamin D and hypertension. Curr Hypertens Rep. 2008;10:49–51
- . 25-hydroxyvitamin D levels and albuminuria in the Third National Health and Nutrition Examination Survey (NHANES III). Am J Kidney Dis. 2007;50:69–77
- Intravenous calcitriol normalizes insulin sensitivity in uremic patients. Kidney Int. 1995;47:200–206
- Effects of atorvastatin on vitamin D levels in patients with acute ischemic heart disease. Am J Cardiol. 2007;99:903–905
- Combination therapy with an angiotensin-converting enzyme inhibitor and a vitamin D analog suppresses the progression of renal insufficiency in uremic rats. J Am Soc Nephrol. 2007;18:1796–1806
- . Combination therapy with paricalcitol and enalapril ameliorated cardiac oxidative injury in uremic rats. Paper presented at: American Society of Nephrology Annual Meeting; 2007;Nov 2-5; San Francisco, CA
- . Racial differences in survival of patients on dialysis. Kidney Int. 2000;58:1293–1299
- . Racial differences in the prevalence and severity of disordered mineral metabolism in chronic kidney disease. Paper presented at: American Society of Nephrology Annual Meeting; 2007;Nov 2-5; San Francisco, CA
- Impact of activated vitamin D and race on survival among hemodialysis patients. J Am Soc Nephrol. 2008;19:1379–1388
- . Active vitamin D and survival. J Am Soc Nephrol. 2008;19:1442–1443
Dr. Patel was supported by National Institutes of Health grant T32-DK07527-23.
PII: S0270-9295(09)00005-9
doi: 10.1016/j.semnephrol.2009.01.004
© 2009 Elsevier Inc. All rights reserved.
« Previous
Next »
Seminars in Nephrology
Volume 29, Issue 2
, Pages 113-121
, March 2009
