Seminars in Nephrology
Volume 30, Issue 1 , Pages 66-73 , January 2010

Kidney Early Evaluation Program: A Community-Based Screening Approach to Address Disparities in Chronic Kidney Disease

  • Joseph A. Vassalotti, MD

      Affiliations

    • National Kidney Foundation and Division of Nephrology, Department of Medicine, Mount Sinai School of Medicine, New York, NY
  • ,
  • Suying Li, PhD

      Affiliations

    • Chronic Disease Research Group, Minneapolis Medical Research Foundation, Minneapolis, MN
  • ,
  • Peter A. McCullough, MD, MPH

      Affiliations

    • William Beaumont Hospital, Detroit, MI
  • ,
  • George L. Bakris, MD

      Affiliations

    • University of Chicago Pritzker School of Medicine, Chicago, IL
    • Corresponding Author InformationAddress reprint requests to George L. Bakris, MD, University of Chicago Pritzker School of Medicine, 5841 S. Maryland Ave, Chicago, IL 60637

References 

  1. Mehrotra R, Kermah D, Fried L, Adler S, Norris K. Racial differences in mortality among those with CKD. J Am Soc Nephrol. 2008;19:1403–1410
  2. Hsu CY, Lin F, Vittinghoff E, Shlipak MG. Racial differences in the progression from chronic renal insufficiency to end-stage renal disease in the United States. J Am Soc Nephrol. 2003;14:2902–2907
  3. Peralta CA, Shlipak MG, Fan D, Ordoñez J, Lash JP, Chertow GM, et al. Risks for end-stage renal disease, cardiovascular events, and death in Hispanic versus non-Hispanic white adults with chronic kidney disease. J Am Soc Nephrol. 2006;17:2892–2899
  4. Kinchen KS, Sadler J, Fink N, Brookmeyer R, Klag MJ, Levey AS, et al. The timing of specialist evaluation in chronic kidney disease and mortality. Ann Intern Med. 2002;137:479–486
  5. Daumit GL, Powe NR. Factors influencing access to cardiovascular procedures in patients with chronic kidney disease: race, sex, and insurance. Semin Nephrol. 2001;21:367–376
  6. US Renal Data System. USRDS 2008 Annual data report: atlas of chronic kidney disease and end-stage renal disease in the United States. Bethesda, MD: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases; 2008;
  7. US Department of Health and Human Services. Healthy people 2010 (With understanding and improving health and objectives for improving health. 2 volumes). 2nd ed.. Washington, DC: US Government Printing Office; 2000;
  8. Norris KC, Agodoa LY. Unraveling the racial disparities associated with kidney disease. Kidney Int. 2005;68:914–924
  9. Powe NR. Let's get serious about racial and ethnic disparities. J Am Soc Nephrol. 2008;19:1271–1275
  10. Jaar BG, Khatib R, Plantinga L, Boulware LE, Powe NR. Principles of screening for chronic kidney disease. Clin J Am Soc Nephrol. 2008;3:601–609
  11. Norris K, Nissenson AR. Race, gender, and socioeconomic disparities in CKD in the United States. J Am Soc Nephrol. 2008;19:1261–1270
  12. Duru OK, Li S, Jurkovitz C, Bakris G, Brown W, Chen SC, et al. Race and sex differences in hypertension control in CKD: results from the Kidney Early Evaluation Program (KEEP). Am J Kidney Dis. 2008;51:192–198
  13. Jurkovitz CT, Qiu Y, Wang C, Gilbertson DT, Brown WW. The Kidney Early Evaluation Program (KEEP): program design and demographic characteristics of the population. Am J Kidney Dis. 2008;51:S3–S12
  14. Collins AJ, Li S, Chen SC, Vassalotti JA. Participant follow-up in the Kidney Early Evaluation Program (KEEP) after initial detection. Am J Kidney Dis. 2008;51(Suppl 2):S69–S76
  15. National Kidney Foundation. K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification and stratification. Am J Kidney Dis. 2002;39(Suppl 1):S1–S266
  16. United States Census Bureau. Census brief. Washington, DC: U.S. Department of Commerce Economics and Statistics Administration; 2002;
  17. Coresh J, Selvin E, Stevens LA, Manzi J, Kusek JW, Eggers P, et al. Prevalence of chronic kidney disease in the United States. JAMA. 2007;298:2038–2047
  18. Jolly SE, Li S, Chen SC, Narva AS, Jurkovitz CT, Norris KC, et al. Risk factors for chronic kidney disease among American Indians and Alaska Natives—findings from the Kidney Early Evaluation Program. Am J Nephrol. 2008;29:440–446
  19. Plantinga LC, Boulware LE, Coresh J, Stevens LA, Miller ER, Saran R, et al. Patient awareness of chronic kidney disease: trends and predictors. Arch Intern Med. 2008;168:2268–2275
  20. Saab G, Whaley-Connell AT, McCullough PA, Bakris GL. CKD awareness in the United States: the Kidney Early Evaluation Program (KEEP). Am J Kidney Dis. 2008;52:382–383
  21. Rao MV, Qiu Y, Wang C, Bakris G. Hypertension and CKD: Kidney Early Evaluation Program (KEEP) and National Health and Nutrition Examination Survey (NHANES), 1999-2004. Am J Kidney Dis. 2008;51(Suppl 2):S30–S37
  22. Whaley-Connell AT, Sowers JR, McFarlane SI, Norris KC, Chen SC, Li S, et al. Kidney Early Evaluation Program Investigators Diabetes mellitus in CKD: Kidney Early Evaluation Program (KEEP) and National Health and Nutrition and Examination Survey (NHANES) 1999-2004. Am J Kidney Dis. 2008;51(Suppl 2):S21–S29
  23. Norris KC, Shlipak MG, Bakris G. KEEP launches follow-up initiative aimed at predicting the future. Nephrol News Issues. 2008;22:44–46

 The Kidney Early Evaluation Program (KEEP) is a program of the National Kidney Foundation, Inc., and is supported by Amgen, Thousand Oaks, CA; Abbott, Abbott Park, IL; Genzyme, Cambridge, MA; Ortho Biotech Products, LP, Horsham, PA; and Novartis, East Hanover, NJ; with additional support provided by Siemens Medical Solutions Diagnostics, Deerfield, IL; Lifescan, Langhorne, PA; Suplena, Abbott, Abbott Park, IL; and OceanSpray Cranberries, Lakeville-Middleboro, MA.

 The authors have no conflicts of interest with the subject matter of this study.

PII: S0270-9295(09)00170-3

doi: 10.1016/j.semnephrol.2009.10.004

Seminars in Nephrology
Volume 30, Issue 1 , Pages 66-73 , January 2010