Advertisement
Research Article| Volume 11, ISSUE 3, P312-319, May 1991

Resident glomerular cells in glomerular injury: Endothelial cells

  • Caroline O.S. Savage
    Correspondence
    Address reprint requests to Caroline O. S. Savage, MD, PhD, Section of Vascular Biology, Clinical Research Centre, Watford Road, Harrow, Middlesex, HA1 3UJ, UK.
    Affiliations
    From the Section of Vascular Biology, Clinical Research Centre, Middlesex, UK

    Department of Renal Medicine, Hammersmith Hospital, London, UK
    Search for articles by this author
  • Richard Bogle
    Affiliations
    From the Section of Vascular Biology, Clinical Research Centre, Middlesex, UK

    Department of Renal Medicine, Hammersmith Hospital, London, UK
    Search for articles by this author
      This paper is only available as a PDF. To read, Please Download here.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Seminars in Nephrology
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Ryan G.B.
        • Majno G.
        Acute inflammation.
        Am J Pathol. 1977; 86: 183-276
        • Rampart M.
        • Williams T.J.
        Polymorphonuclear leukocyte-dependent plasma leakage in rabbit skin is enhanced or inhibited by prostacyclin, depending on the route of administration.
        Am J Pathol. 1986; 124: 66-73
        • Moncada S.
        • Gryglewski R.
        • Bunting S.
        • et al.
        An enzyme isolated from arteries transforms prostacyclin endoperoxides to an unstable substance that inhibits platelet aggregation.
        Nature. 1976; 263: 663-665
        • Tateson J.E.
        • Moncada S.
        • Vane J.R.
        Effects of prostacyclin (PGX) on cyclic AMP concentrations in human platelets.
        Prostaglandins. 1977; 13: 389-397
        • Hallam T.J.
        • Pearson J.D.
        • Needham L.A.
        Thrombin-stimulated elevation of human endothelial-cell cytoplasmic free calcium concentration causes prostacyclin production.
        Biochem J. 1988; 251: 243-249
        • Moscat J.
        • Moreno F.
        • Herrero C.
        • et al.
        Arachidonic acid releasing systems in pig aortic endothelial cells.
        Biochem Biophys Res Commun. 1986; 139: 1098-1103
        • McIntyre T.M.
        • Zimmerman G.A.
        • Satch K.
        • et al.
        Cultured endothelial cells synthesize both platelet activating factor and prostacyclin in response to histamine, bradykinin and adenosine triphosphate.
        J Clin Invest. 1985; 76: 271-280
        • Pearson J.D.
        • Carleton J.S.
        • Hutchings A.
        Prostacyclin release stimulated by thrombin or bradykinin in porcine endothelial cells cultured from aorta and umbilical cord.
        Thrombosis Res. 1983; 29: 1181-1190
        • Needham L.
        • Cusack N.J.
        • Pearson J.D.
        • et al.
        Characteristics of the P2 purinoreceptor that mediates prostacyclin production by pig aortic endothelial cells.
        Eur J Pharmacol. 1987; 134: 199-209
        • Naworth P.P.
        • Stern D.M.
        Modulation of endothelial cell hemostatic properties by tumor necrosis factor.
        J Exp Med. 1986; 163: 740-745
        • Zavoico G.B.
        • Ewenstein B.M.
        • Schafer A.I.
        • et al.
        IL-1 and related cytokines enhance thrombin-stimulated PGI2 production in cultured endothelial cells without affecting thrombinstimulated von Willebrand factor secretion or platelet-activating factor biosynthesis.
        J Immunol. 1989; 142: 3993-3999
        • Palmer R.M.J.
        • Ferrige A.G.
        • Moncada S.
        Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor.
        Nature. 1987; 327: 524-526
        • Palmer R.M.J.
        • Ashton D.S.
        • Moncada S.
        Vascular endothelial cells synthesize nitric oxide from l-arginine.
        Nature. 1988; 333: 664-666
        • Schmidt H.H.H.W.
        • Nall H.
        • Wittfoht W.
        • et al.
        l-arginine is the physiological precursor of endothelium-derived nitric oxide.
        Eur J Pharmacol. 1988; 154: 213-216
        • Busse R.
        • Mulsch A.
        Calcium dependent nitric oxide synthesis in endothelial cytosol is modulated by calmodulin.
        FEBS Lett. 1990; 265: 133-136
        • Palmer R.M.J.
        • Moncada S.
        A novel citrulline-forming enzyme implicated in the formation of nitric oxide in vascular endothelial cells.
        Biochem Biophys Res Commun. 1990; 158: 348-352
        • Luckhoff A.
        • Pohl U.
        • Mulsch A.
        • et al.
        Differential role of extra and intracellular calcium in the release of EDRF and prostacyclin from cultured endothelial cells.
        Br J Pharmacol. 1988; 95: 189-195
        • de Nucci G.
        • Gryglewski R.J.
        • Warner T.J.
        • et al.
        Receptor mediated release of endothelium derived relaxing factor from bovine aortic endothelial cells is coupled.
        in: Proc Natl Acad Sci USA. 85. 1988: 2334-2338
        • Arnold W.P.
        • Mittal C.K.
        • Katsuki S.
        • et al.
        Nitric oxide activates guanylate cyclase and increases guanosine 3′5′-cyclic monophosphate in isolated tissue preparations.
        in: Proc Natl Acad Sci USA. 14. 1977: 3203-3207
        • Shultz P.J.
        • Schorer A.E.
        • Raij L.
        Effects of endotheliumderived relaxing factor and nitric oxide on rat mesangial cells.
        Am J Physiol (Renal Fluid Electrolyte Physiol 27). 1990; 258: F162-F167
        • Kilbourn R.G.
        • Belloni P.
        Endothelial cell production of nitrogen oxides in response to interferon-gamma in combination with tumor necrosis factor, interleukin-1, and endotoxin.
        J Natl Cancer Inst. 1990; 82: 772-776
        • Rees D.D.
        • Palmer R.M.J.
        • Hodson H.F.
        • et al.
        A specific inhibitor of nitric oxide formation from l-arginine attenuates endothelium dependent relaxation.
        Br J Pharmacol. 1989; 96: 418-424
        • Yanagisawa M.
        • Kurihara H.
        • Kimura S.
        A novel potent vasoconstrictor peptide produced by vascular endothelial cells.
        Nature. 1988; 332: 411-415
        • Inoue A.
        • Yanagisawa M.
        • Kimuira S.
        • et al.
        The human endothelin family: Three structurally and pharmacologically different isopeptides predicted by three separate genes.
        in: Proc Natl Acad Sci USA. 86. 1989: 2863-2867
        • Pernow J.
        • Franco-Cereceda A.
        • Matran R.
        • et al.
        Effects of endothelin-1 on regional vascular resistance in the pig.
        J Cardiovasc Pharmacol Suppl. 1989; 5: S205-S206
        • Kon V.
        • Yoshioka T.
        • Fogo A.
        • et al.
        Glomerular actions of endothelin in vivo.
        J Clin Invest. 1989; 83: 1762-1767
        • Berk B.C.
        • Alexander R.W.
        • Brock T.A.
        • et al.
        Vasoconstriction: A new activity for platelet-derived growth factor.
        Science. 1986; 232: 87-90
        • Harlan J.M.
        • Thompson P.J.
        • Ross R.R.
        • et al.
        α-thrombin induces release of platelet-derived growth factor-like molecule(s) by cultured human endothelial cells.
        J Cell Biol. 1986; 103: 1129-1133
        • Daniel T.O.
        • Gibbs V.C.
        • Milfary D.F.
        • et al.
        Thrombin stimulates C-sis gene expression in microvascular endothelial cells.
        J Biol Chem. 1986; 261: 9579-9582
        • Hajjar K.A.
        • Hajjar D.P.
        • Silverstein R.L.
        • et al.
        Tumor necrosis factor-mediated release of platelet-derived growth factor from cultured endothelial cells.
        J Exp Med. 1987; 166: 235-245
        • Rees D.D.
        • Palmer R.M.J.
        • Moncada S.
        Role of endothelium-derived nitric oxide in the regulation of blood pressure.
        in: Proc Natl Acad Sci USA. 86. 1989: 3375-3378
        • Beasley D.
        • Cohen R.A.
        • Levinsky N.G.
        Interleukin 1 inhibits contraction of vascular smooth muscle.
        J Clin Invest. 1989; 83: 331-335
        • Knowles R.G.
        • Merrett M.
        • Salter M.
        • et al.
        Differential induction of brain, lung, and liver nitric oxide synthase by endotoxin in the rat.
        Biochem J. 1990; 270: 833-836
        • Knowles R.G.
        • Salter M.
        • Brooks S.L.
        • et al.
        Anti-inflammatory glucocorticoids inhibit the induction by endotoxin of nitric oxide synthase in the lung, liver, and aorta of the rat.
        Biochem Biophys Res Commun. 1990; 172: 1042-1048
        • Wedmore C.V.
        • Williams T.J.
        Control of vascular permeability by polymorphonuclear leukocytes in inflammation.
        Nature (Lond). 1981; 289: 646-650
        • Majno G.
        • Shea S.M.
        • Leventhal M.
        Endothelial contraction induced by histamine-type mediators: An electron microscopic study.
        J Cell Biol. 1969; 42: 647-672
        • Wysolmerski R.B.
        • Lagunoff D.
        Involvement of myosin light chain kinase in endothelial cell retraction.
        in: Proc Natl Acad Sci USA. 87. 1990: 16-20
        • Dahlen S.
        • Bjork J.
        • Hedqvist P.
        • et al.
        Leukotrienes promote plasma leakage and leukocyte adhesion in post-capillary venules: In vivo effects with relevance to the acute inflammatory response.
        in: Proc Natl Acad Sci USA. 78. 1981: 3887-3891
        • Stolpen A.H.
        • Guinan E.C.
        • Fiers W.
        • et al.
        Recombinant tumor necrosis factor and immune interferon act singly and in combination to reorganize human vascular endothelial cell monolayers.
        Am J Pathol. 1986; 123: 16-24
        • Fanger M.W.
        • Shen L.
        • Graziano R.F.
        • et al.
        Cytotoxicity mediated by human Fc receptors for IgG.
        Immunol Today. 1989; 10: 92-99
        • Varani J.
        • Ginsburg I.
        • Schuger L.
        • et al.
        Endothelial cell killing by neutrophils: Synergistic interaction of oxygen products and proteases.
        Am J Pathol. 1989; 135: 435-438
        • Peters P.J.
        • Geuze H.J.
        • Van der Donk H.A.
        • et al.
        A new model for lethal hit delivery by cytotoxic T lymphocytes.
        Immunol Today. 1990; 11: 28-32
        • Nawroth P.P.
        • Handley D.A.
        • Eamon C.T.
        • et al.
        Interleukin 1 induces endothelial procoagulant while suppressing cell surface anticoagulant activity.
        in: Proc Natl Acad Sci. 83. 1986: 3460-3464
        • Varani J.
        • Bendelow M.J.
        • Sealey D.E.
        • et al.
        Tumor necrosis factor enhances susceptibility of vascular endothelial cells to neutrophil-mediated killing.
        Lab Invest. 1988; 59: 292-295
        • Hattori R.
        • Hamilton K.K.
        • Fugate R.D.
        • et al.
        Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140.
        J Biol Chem. 1989; 264: 7768-7771
        • Geng J.C.
        • Bevilacqua M.P.
        • Moore K.L.
        • et al.
        Rapid neutrophil adhesion to activated endothelium mediated by GMP-140.
        Nature (Lond). 1990; 343: 757-760
        • Stoolman L.M.
        Mini review: Adhesion molecules controlling lymphocyte migration.
        Cell. 1989; 56: 907-910
        • Geoffrey J.S.
        • Rosen S.D.
        Demonstration that a lectin-like receptor (gp90MEL) directly mediated adhesion of lymphocytes to high endothelial venules of lymph nodes.
        J Cell Biol. 1989; 109: 2463-2469
        • Jutila M.A.
        • Rott L.
        • Berg E.L.
        • et al.
        Function and regulation of the neutrophil MEL-14 antigen in vivo: Comparison with LEA-1 and Mac-1.
        J Immunol. 1989; 143: 3318-3324
        • Tonnesen M.G.
        • Anderson D.C.
        • Springer T.A.
        • et al.
        Adherence of neutrophils to cultured human microvascular endothelial cells: Stimulation by chemotactic peptides and lipid mediators and dependence upon the Mac-1, LFA-1, p150,95 glycoprotein family.
        J Clin Invest. 1989; 83: 637-646
        • Figdor C.G.
        • van Kooyk Y.
        • Keizer G.D.
        On the mode of action of LFA-1.
        Immunol Today. 1990; 11: 277-280
        • Smith C.W.
        • Rothlein R.
        • Hughes B.J.
        • et al.
        Recognition of an endothelial determinant for CD18-dependent human neutrophil adherence and transendothelial migration.
        J Clin Invest. 1988; 82: 1746-1756
        • Smith C.W.
        • Marlin S.D.
        • Rothlein R.
        • et al.
        Co-operative interactions of LFA-1 and Mac-1 with intercellular adhesion molecule-I in facilitating adherence and transendothelial migration of human neutrophils in vitro.
        J Clin Invest. 1989; 83: 2008-2017
        • Bevilacqua M.P.
        • Pober J.S.
        • Mendrick D.L.
        • et al.
        Identification of an inducible endothelial-leukocyte adhesion molecule.
        in: Proc Natl Acad Sci USA. 84. 1987: 9238-9242
        • Bevilacqua M.P.
        • Stengelin S.
        • Gimbrone Jr, M.A.
        • et al.
        Endothelial leukocyte adhesion molecule 1: An inducible receptor for neutrophils related to complement regulatory proteins and lectins.
        Science Wash DC. 1989; 243: 1160-1165
        • Lowe J.B.
        • Stoolman L.M.
        • Nair R.P.
        • et al.
        ELAM-1-dependent cell adhesion to vascular endothelium determined by a transfected human fucosyltransferase cDNA.
        Cell. 1990; 63: 475-484
        • Cotran R.S.
        • Gimbrone Jr, M.A.
        • P B.M.
        • et al.
        Induction and detection of a human endothelial activation antigen in vivo.
        J Exp Med. 1986; 164: 661-666
        • Strieter R.M.
        • Kunkel S.L.
        • Showell H.J.
        • et al.
        Endothelial cell gene expression of a neutrophil chemotactic factor by TNF-alpha, LPS, and IL-1beta.
        Science. 1989; 243: 1467-1469
        • Gimbrone Jr, M.A.
        • Obin M.S.
        • Brock A.F.
        • et al.
        Endothelial interleukin-8: A novel inhibitor of leukocyte-endothelial interactions.
        Science. 1989; 246: 1601-1603
        • Matsushima K.V.
        • Oppenheim J.J.
        Review article: Interleukin 8 and MCAF: Novel inflammatory cytokines induced by TNF and IL-1.
        Cytokine. 1989; 1: 2-10
        • Detmers P.A.
        • Los K.
        • Olsen-Egbort E.
        • et al.
        Neutrophil-activating protein 1/Interleukin 8 stimulates the binding activity of the leukocyte adhesion receptor CD 11b/CD18 on human neutrophils.
        J Exp Med. 1990; 171: 1155-1162
        • Kishimoto T.K.
        • Jutila M.A.
        • Butcher E.C.
        Identification of a human peripheral lymph node homing receptor: A rapidly down regulated adhesion molecule.
        in: Proc Nad Acad Sci USA. 87. 1990: 2244-2248
        • Pober J.S.
        • Gimbrone Jr, M.A.
        • Lapierre L.A.
        • et al.
        Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor and immune interferon.
        J Immunol. 1986; 137: 1893-1896
        • Munro J.M.
        • Pober J.S.
        • Cotran R.S.
        Tumor necrosis factor and interferon-gamma induce distinct patterns of endothelial activation and leukocyte accumulation in skin of Papio anubis.
        Am J Pathol. 1989; 135: 121-133
        • Osborn L.
        • Hession R.
        • Tizard R.
        • et al.
        Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds lymphocytes.
        Cell. 1989; 59: 1203-1211
        • Rice G.E.
        • Bevilacqua M.P.
        An inducible endothelial cell surface glycoprotein mediates melanoma adhesion.
        Science Wash DC. 1989; 246: 1303-1306
        • Rice G.E.
        • Munro J.M.
        • Bevilacqua M.P.
        Inducible cell adhesion molecule 110 (INCAM-110) is an endothelial receptor for lymphocytes: A CD11/CD18-independent adhesion mechanism.
        J Exp Med. 1990; 171: 1369-1374
        • Thornhill M.H.
        • Haskard D.O.
        IL-4 regulates endothelial cell activation by IL-1, tumor necrosis factor, or IFN-gamma.
        J Immunol. 1990; 145: 865-872
        • Dustin M.L.
        • Staunton D.E.
        • Springer T.A.
        Supergene families meet in the immune system.
        Immunol Today. 1988; 9: 213-215
        • Stanton D.E.
        • Dustin M.L.
        • Springer T.A.
        Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1.
        Nature (Lond). 1989; 339: 61-64
        • Elices M.J.
        • Osborn L.
        • Takada Y.
        • et al.
        VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site.
        Cell. 1990; 60: 577-584
        • Schwartz B.R.
        • Wayner E.A.
        • Carlos T.M.
        • et al.
        Identification of surface proteins mediating adherence of CD1 l/CD18deficient lymphoblastoid cells to cultured human endothelium.
        J Clin Invest. 1990; 85: 2019-2022
        • Albelda S.M.
        • Buck C.A.
        Integrins and other cell adhesion molecules.
        FASEB J. 1990; 4: 2868-2880
        • Dustin M.L.
        • Springer T.A.
        T cell receptor cross-linking transiently stimulates adhesiveness through LFA-1.
        Nature. 1989; 341: 619-624
        • Van Epps D.E.
        • Potter J.
        • Vachula M.
        • et al.
        Suppression of human lymphocyte chemotaxis and transendothelial migration by anti-LFA-1 antibody.
        J Immunol. 1989; 143: 3207-3210
        • Streiter R.M.
        • Wiggins R.
        • Phan S.H.
        • et al.
        Monocyte chemotactic protein gene expression by cytokine-treated human fibroblasts and endothelial cells.
        Biochem Biophys Res Commun. 1989; 162: 694-699
        • Sica A.
        • Wang J.M.
        • Colotta F.
        • et al.
        Monocyte chemotactic and activating factor gene expression induced in endothelial cells by IL-1 and tumor necrosis factor.
        J Immunol. 1989; 144: 3034-3038
        • Rollins B.J.
        • Yoshimura T.
        • Leonard E.J.
        • et al.
        Cytokine-activated human endothelial cells synthesize and secrete a monocyte chemoattractant, MCP-1/JE.
        Am J Pathol. 1990; 136: 1229-1233
        • Damle N.K.
        • Doyle L.V.
        Ability of human T lymphocytes to adhere to vascular endothelial cells and to augment endothelial permeability to macromolecules is linked to their state of post-thymic maturation.
        J Immunol. 1990; 144: 1233-1240
        • Sanders M.E.
        • Makgoba M.W.
        • Sharrow S.O.
        • et al.
        Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA-1) and three other molecules (UCHL 1, CDw29, and Pgp-1) and have enhanced IFN-gamma production.
        J Immunol. 1988; 140: 1401-1407
        • Jalkanen S.
        • Bargatze R.F.
        • de los Toyos J.
        • et al.
        Lymphocyte recognition of high endothelium: Antibodies to distinct epitopes of an 85–95-kD glycoprotein antigen differentially inhibit lymphocyte binding to lymph node, mucosal, or synovial endothelial cells.
        J Cell Biol. 1987; 105: 983-990
        • Pober J.S.
        • Gimbrone Jr, M.A.
        • Cotran R.S.
        • et al.
        Ia expression by vascular endothelium is inducible by activated T cells and by human gamma-interferon.
        J Exp Med. 1983; 157: 1339-1353
        • Collins T.
        • Korman A.J.
        • Wake C.T.
        • et al.
        Immune interferon activates multiple class II major histocompatibility complex genes and the associated invariant chain gene in human endothelial cells and dermal fibroblasts.
        in: Proc Natl Acad Sci USA. 81. 1984: 4917-4921
        • Pober J.S.
        • Collins T.
        • Gimbrone Jr, M.A.
        • et al.
        Lymphocytes recognize human vascular endothelial and dermal fibroblast la antigens induced by recombinant immune interferon.
        Nature (Lond). 1983; 305: 726-729
        • Pober J.S.
        • Collins T.
        • Gimbrone Jr, M.A.
        • et al.
        Inducible expression of class II major histocompatibility complex antigens and the immunogenicity of vascular endothelium.
        Transplantation Baltimore. 1986; 41: 141-146
        • Wagner C.R.
        • Vetto R.M.
        • Burger D.R.
        Expression of I-Region-Associated Antigen (Ia) and interleukin 1 by subcultured human endothelial cells.
        Cell Immunol. 1985; 93: 91-104
        • Hughes C.C.W.
        • Savage C.O.S.
        • Pober J.S.
        The endothelial cell as a regulator of T -cell function.
        Immunol Rev. 1990; 117: 85-102
        • Doukas J.
        • Pober J.S.
        IFN-γ enhances endothelial activation induced by TNF but not IL-1.
        J Immunol. 1990; 145: 1727-1733
        • Luster A.D.
        • Unkeless J.C.
        • Ravetch J.V.
        γ-interferon transcriptionally regulates an early-response gene containing homology to platelet proteins.
        Nature (Lond). 1985; 315: 672-675
        • Hancock W.W.
        • Cotran R.S.
        Induction of activation antigens on human glomerular endothelium by interleukin 1, interferon gamma, and endotoxin.
        Kidney Int. 1987; 31 (abstr): 322