Advertisement

Introduction: Complement-Mediated Kidney Diseases

      Recent years have witnessed a resurgence of interest in the complement system and its regulation. This interest is in no small part the result of discoveries regarding the role of complement in several forms of kidney disease and in the alloimmune response to organ transplantation.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Seminars in Nephrology
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

      1. Hegasy GA, Manuelian T, et al. The molecular basis for hereditary porcine membranoproliferative glomerulonephritis type II: point mutations in the factor H coding sequence block protein secretion. Am J Pathol. 2002;161:2027-34.

      2. Pickering MC, Cook HT, et al. Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H. Nat Genet. 2002;31;424-8.