Advertisement

Introduction: Sex and Gender in Kidney Health and Disease: Time for a Paradigm Shift

  • Sofia B. Ahmed
    Affiliations
    Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada
    Alberta Kidney Disease Network, Calgary, Alberta, Canada
    Libin Cardiovascular Institute, Calgary, Alberta, Canada
    O'Brien Institute for Public Health, Calgary, Alberta, Canada
    Search for articles by this author
      Kidney disease is a global epidemic and innovations in prevention and treatment are urgently needed. However, current practices in kidney research and care often use a one-size-fits-all approach, which does not address the specific sex- and gender-based differences in physiology, pathophysiology, presentation, choice of therapies, and response to treatments, all of which impact outcomes.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Seminars in Nephrology
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      REFERENCES

        • García GG
        • Iyengar A
        • Kaze F
        • et al.
        Sex and gender differences in chronic kidney disease and access to care around the globe.
        Semin Nephrol. 2022; 42: 101-113
        • Quinlan C
        • Rheault MN
        X-Linked kidney disorders in women.
        Semin Nephrol. 2022; 42: 114-121
        • Hecking M
        • Hödlmoser S
        • Ahmed SB
        • Carrero JJ
        The other way around: living with chronic kidney disease from the perspective of men.
        Semin Nephrol. 2022; 42: 122-128
        • Collister D
        • Krakowsky Y
        • Potter E
        • Millar AC
        Chronic kidney disease in the transgender, nonbinary, or gender diverse person.
        Semin Nephrol. 2022; 42: 129-141
        • Dumanski SM
        • Eckersten D
        • Piccoli GB
        Reproductive health in chronic kidney disease: the implications of sex and gender.
        Semin Nephrol. 2022; 42: 142-152
        • Wyld MLR
        • Mata NLDL
        • Viecelli A
        • et al.
        Sex-based differences in risk factors and complications of chronic kidney disease.
        Semin Nephrol. 2022; 42: 153-169
        • Sridhar VS
        • Yau K
        • Benham JL
        • et al.
        Sex and gender related differences in diabetic kidney disease.
        Semin Nephrol. 2022; 42: 170-184
        • Beckwith H
        • Lightstone L
        • McAdoo S
        Sex and gender in glomerular disease.
        Semin Nephrol. 2022; 42: 185-196
        • Yi TW
        • Levin A
        Sex, gender, and cardiovascular disease in chronic kidney disease.
        Semin Nephrol. 2022; 42: 197-207
        • Neugarten J
        • Golestaneh L
        Sex differences in acute kidney injury.
        Semin Nephrol. 2022; 42: 208-218
        • Katz-Greenberg G
        • Shah S
        Sex and gender differences in kidney transplantation.
        Semin Nephrol. 2022; 42: 219-229
        • Ferraro PM
        • Cunha TdS
        • Curhan GC
        Sex differences and the risk of kidney stones.
        Semin Nephrol. 2022; 42: 230-235
      1. Science is better with sex and gender. Canadian Instititutes of Health Research Institute of Gender and Health Strategic Plan 2018-2023. 2022. Accessed May 16, 2022. https://cihr-irsc.gc.ca/e/51310.html.

      2. World kidney day 2022: kidney health for all. Accessed May 16, 2022. https://www.worldkidneyday.org.