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Review Article| Volume 42, ISSUE 5, 151319, September 2022

Use of Medicinal Plants in Africa: A Case Study From the Democratic Republic of Congo (DRC)

  • Chantal Zinga
    Correspondence
    Address reprint requests to Chantal Zinga, MSc, Division of Nephrology, Department of Internal Medicine, Faculty of Medicine, Université de Kinshasa, PO Box 123, Kinshasa, XI, Democratic Republic of Congo.
    Affiliations
    Division of Nephrology, Department of Internal Medicine, Faculty of Medicine, Université de Kinshasa, Kinshasa, XI, Democratic Republic of Congo

    Unit of Clinical Pharmacology and Pharmacovigilance, Faculty of Medicine and Pharmaceutical Sciences, Université de Kinshasa, Kinshasa, XI, Democratic Republic of Congo

    Organic Chemistry and Energetic Laboratory, Department of Chemistry and Industry, Faculty of Science, Université de Kinshasa, Kinshasa, XI, Democratic Republic of Congo
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  • Kalulu Taba
    Affiliations
    Organic Chemistry and Energetic Laboratory, Department of Chemistry and Industry, Faculty of Science, Université de Kinshasa, Kinshasa, XI, Democratic Republic of Congo
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  • Gauthier Mesia
    Affiliations
    Unit of Clinical Pharmacology and Pharmacovigilance, Faculty of Medicine and Pharmaceutical Sciences, Université de Kinshasa, Kinshasa, XI, Democratic Republic of Congo
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  • Ernest Sumaili
    Affiliations
    Division of Nephrology, Department of Internal Medicine, Faculty of Medicine, Université de Kinshasa, Kinshasa, XI, Democratic Republic of Congo
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  • Gaston Tona
    Affiliations
    Unit of Clinical Pharmacology and Pharmacovigilance, Faculty of Medicine and Pharmaceutical Sciences, Université de Kinshasa, Kinshasa, XI, Democratic Republic of Congo
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  • Jean-Jacques Muyembe
    Affiliations
    Institut National de Recherche Biomédicale, Division of Microbiology, Medical Biology, Faculty of Medicine, Université de Kinshasa, Kinshasa, XI, Democratic Republic of Congo
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  • Junior Kindala
    Affiliations
    Organic Chemistry and Energetic Laboratory, Department of Chemistry and Industry, Faculty of Science, Université de Kinshasa, Kinshasa, XI, Democratic Republic of Congo
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  • Nazaire Nseka
    Affiliations
    Division of Nephrology, Department of Internal Medicine, Faculty of Medicine, Université de Kinshasa, Kinshasa, XI, Democratic Republic of Congo
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      Summary

      Although medicinal plants are beneficial, they also can be important risk factors for the development of acute and chronic kidney injury, as well toxicity of other solid organs. There are a lack of reports of adverse kidney events and drug interactions resulting from medicinal plants owing to a lack of professional surveillance and specific data on kidney toxicity, especially in low-resource settings. Within the context of increased medicinal plant use and lack of effective regulatory control, safety is a key priority issue. We review the benefits and adverse effects of medicinal plants with particular reference to nephrotoxicity encountered in the Democratic Republic of Congo in sub-Saharan Africa.

      Keywords

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